Research Groups | The Laboratory for Molecular Genetics and Pharmacogenetics | Dr. Dani Bercovich

After high school served in the Navy for 4.5 years as a Frogman.

  • 1984 – 1988 Agriculture worker.

Academic background

  • 1988 - 1991 Faculty of Agriculture Hebrew University
    B.Sc. Animal Science (with distinction)
  • 1992 - 1993 Faculty of Agriculture Hebrew University
    M.Sc. Feed Control (with distinction)
  • 1994 - 1998 Genetics Department  Hebrew University and Molecular Genetics MIGAL (Galilee Technology Center) Ph.D.
  • 1998 - 1999 MIGAL Postdoctoral Human Molecular Genetics
  • 1999 - 2001Baylor College of MedicineHuman Molecular Houston, TxPostdoctoralGenetics DHPLC mutation Analysis in human. Mice-knockout
  • 2001 MIGAL Head of the Molecular Genetics Molecular Genetics DHPLC screening Department
  • 2001 Sourasky Medical PIGenetics testing Center development with the DHPLC
Research & Teaching Experience
  • 1994 MIGAL ResearchAnimal breeding.Hebrew Universitydevelpoment & quantiteayive genetics.
  • Baylor College of Medicine Human Molecular genetics. Knokout mice DHPLC
  • 1995 Tel-Hai Academic College InstructBasic genetics Molecular genetics & Genetic engineering
  • 1998 Ohallo College Lecture Cell Biology
  • 2001 Tel-Hai Academic College Lecture  Basic genetics Molecular genetics & Genetic engineering
Publications:
  • Bercovich, D., Regev, Z., Ratz, T. and Plotsky, Y. 1997. The effect of quantitative ratio between primer pairs on PCR products in multi-band  amplification. Modern Applications of  DNA Amplification Techniques, Edited by Lassner et al., Plenum Press York: 83-89.
  • Bercovich, D., Plotsky, Y. and Gruenbaum Y. 1999. Improved protocol for using avian red blood cells as substrates for the polymerase chain reaction. Biotechniques. Jun;26(6):1080-2.
  • Bercovich, D., Regev, R., Ratz, T., Gruenbaum, Y., Luder, A. and Plotsky, Y. 1999. The Quantitative Ratio of Primer Paris and Annealing Temperature Affect PCR Products in  Multi-Band Amplification. Biotechniques  Oct;27(4):762-4, 766-8, 770.
  • Bercovich D. 2001. Identification of mutation in the UBE3A gene in Angelman patient using Denaturing High Performance Liquid  Chromatography (DHPLC). In: Scriver SR, Beaudet AL, Valle D, Sly WS, Childs B, Kinzler KW, Vogelstein B editors. The metabolic and molecular bases of inherited disease. New York: McGraw-Hill,:14.
  • Bercovich D. and Beaudet AL. 2002. Denaturing High Performance Liquid Chromatography (DHPLC) for the detection of mutations and polymorphisms in the UBE3A gene. Genetics Testing (submitted).
  • Liran I. Shlush, Doron M. Behar, Adrian Zelazny, Nathy Keller, James R. Lupski, Arthur L. Beaudet and Dani Bercovich.. Molecular Epidemiological analysis of the Changing Nature of a Meningococcal Outbreak Following a Vaccination Campaign. JCM, 2002; 3: 40.
  • Rennert H, Bercovich D, Hubert A, Abeliovich D, Rozovsky U, Bar-Shira A, Soloviov S, Schreiber L, Matzkin H, Rennert G, Kadouri L, Peretz T, Yaron Y, Orr-Urtreger A. A Novel Founder Mutation in the RNASEL Gene, 471delAAAG, Is Associated with Prostate Cancer in Ashkenazi Jews. Am J Hum Genet 2002 Jul 23;71(4).
  • Gavert N, Yaron Y, Naiman T, Bercovich D, Rozen P, Shomrat R, Legum C, Orr-Urtreger A. Molecular analysis of the APC gene in 71 Israeli families: 17 novel mutations. Hum Mutat 2002 Jun;19(6):664
  • Yuval Yaron, Bruria Ben Zeev, Ruth Shomrat, Dani Bercovich, Tova Naiman, Avi            Orr-Urtreger. MECP2 Mutations in Israel: Implications for Molecular Analysis, Genetic Counseling and Prenatal Diagnosis in Rett Syndrome. Hum Mut. 2002 (submitted).
  • Ofer Lehavi , Orna Aizenstein ,Dani Bercovich, Dina Pavzner, Ruth Shomrat, Avi Orr-Urtreger,Yuval Yaron. Screening for familial dysautonomia Israel: evidence for higher carrier rate among Polish Ashkenazi Jews. Submitted to Genetic Testing, July 15, 2002
  • Efrat Lev-Lehman, Dani Bercovich, Wei Xu, and Arthur L. Beaudet. 2001. Characterization of the human 4 nicotinic acetylcholine receptor gene (CHRNB4) and polymorphisms in CHRNA3 and CHRNB4. J hum Genet 46:362-366.
  • Bodamer AO, Bercovich D, Schlabach M, Ballantyne C, Zoch D, and Beaudet AL. 2002 Familial Hypercholesterolemia - Rapid and Cost-Effective Diagnosis by Denaturing HPLC and Direct Sequencing. Clinical Chemistry (in press).
  • Arredondo J, Nguyen V, Chernyavsky AI, Bercovich D, Orr-Urtreger A, Kummer W, Lips K, Vetter DE, Beaudet AL and Grando SA. 2002. Central role of a7 nicotinic receptor in differentiation of the stratified squamous epithelium. JCB. (submitted).
  • Pitcovski, J., Ohana, N., Amzaleg, S., Krispel, D., Bercovich D. andPinchasov, Y. (1997). Identification of a starting point of breast skin tears during chicken plucking. Poultry Science, 76: 405-409.
  • Pitcovski, J. Bercovich, D. Azar, M. Gotfrid, Y. and Bendhaim U. (1998). Comparison of raising budgerigars by both parents or by the male only. Journal of Avian Medicine & Surgery. 12(4):263-267.
Oral presentations
  • Bercovitz, D., Plotsky, Y., Ratz, T., Tsilkin, G., Yaakobi, M. and Gruenbaum, Y. 1997. The Homeobox Gene CdxA and quantitative traits in broiler lines. 35-TH Ann. Conv., World’s Poultry Science Assoc., Zichron Yaacov, p. 114. (Awarded by the WPSA).
  • Bercovich, D., Regev, R., Ratz, T., and Plotsky, Y. (1997). The Quantitative Ratio of Primer Paris and Annealing Temperature Affect PCR  Products in  Multi-Band Amplification. Modern Applications of  DNA Amplification Techniques, Bellem, East Germany, Septe. 1997.
  • Bercovich D. and Beaudet A.L. (2000) Denaturing High Performance Liquid Chromatography (DHPLC) and Diagnosis of DNA Alterations. 50-ASHG, Philadelphia,  Transgenomic symposium.
  • Bercovich D. and Beaudet A.L. (2000). Using the Denaturing High Performance      Liquid Chromatography (DHPLC) and Diagnosis of DNA Alterations. Georgia       Genetics Symposium II: Mutagenesis of the Mouse Genom. Sep. 2000.
  • Bercovich D. and Beaudet A.L. (2001). Denaturing High Performance Liquid Chromatography (DHPLC) for screening of DNA Alterations. Genomics3. Houston, April 2001.
  • Dani Bercovich,  Juan Arredondo,  Vu Thuong Nguyen, Leon H. Hall, Alexander I. Chernyavsky,  Avi Orr-Urtreger,  Wolfgang Kummer,  Katrin Lips,  Douglas E. Vetter,  Arthur L Beaudet, and Sergei A. Grando Nicotinic receptor knockout mice: cholinergic dysfunction in non-neuronal cells. nAChR in non-neuronal cells symposium. San Francisco 2002.
Posters presentations
  • Bercovich, D.  E. Lev-Lehman, A. L. Beaudet. (2000). Denaturing High Performance  Liquid Chromatography (DHPLC)used in  the detection of mutations and polymorphism in the UBE3A gene. 50- ASHG, 1339.
  • Bercovich D. and Beaudet A.L. (2000). Denaturing High Performance Liquid Chromatography (DHPLC) used in the detection of mutation and polymorphism’s in the UBE3A, MECP2 and PLCB13 Genes. Hum, Mol Gen, Reatrit. 49.
  • E. Lev-Lehman, D. Bercovich, W. Xu, A. L. Beaudet. (2000). Megacystic, Microcolon, Hypoperistalsis (MIMIHS) and Pseudo-Obstruction  Syndrome: Searching for the human genes. 50-ASHG, 2192.
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