Cellular Immunotherapy & SynBio

Dr Hadas Weinstein-Marom

Cannabidiol polarizes human neutrophils toward a cancer-promoting phenotype

Mona Khoury, Yuxiang Hong, Dayana Blokon-Kogan, Stela Gengrinovitch, Harel Eitam, Moran Avraham-Kelbert, Hadas Weinstein-Marom, Peng Xu, Idan Cohen, Gil Bar-Sela
Front. Immunol., 25 July 2025
2025

CD32B1, a versatile non-signaling antibody-binding scaffold for enhanced T cell adhesion to tumor stromal cognate antigens

Feigelson, S. W., Dadosh, T., Sapoznikov, A., Weinstein-Marom, H., Blokon-Kogan, D., Avraham, Y., Unger, T., Gross, G., Dahan, R. and Alon. R.
Front. Immunol., Vol. 15.
2025

Regulatory CD4+ T cells redirected against pathogenic CD8+ T cells protect NOD mice from development of autoimmune diabetes

Kakabadse, D., Chen, D., Fishman, S., Weinstein-Marom, H., Davies, J., Wen, L., Gross, G. & Wong, F.S.
Frontiers in Immunology. 15:1463971
2024

Novel engineered B lymphocytes targeting islet-specific T cells inhibit the development of type 1 diabetes in non-obese diabetic Scid mice

Dawei Chen, Dimitri Kakabadse, Sigal Fishman, Hadas Weinstein-Marom, Joanne Davies, Joanne Boldison, Terri C Thayer, Li Wen, Gideon Gross, F Susan Wong
Front. Immunol. Sep. 4.
2023

Membrane anchored IL-18 linked to constitutively active TLR4 and CD40 improves human T cell antitumor capacities for adoptive cell therapy

Blokon-Kogan, D., Levi- Mann, D., Malka-Levy, L., Itzhaki, O., Besser, M.J., Shiftan, Y., Szöőr, Á., Vereb, G., Gross, G., Abken, H. and Weinstein-Marom, H.
J. Immunother. Cancer, July 23.
2022

Genetic Modification of Tumor-Infiltrating Lymphocytes via Retroviral Transduction

Weinstein-Marom, H., Gross, G., Levi, M., Brayer, H., Schachter, J., Itzhaki, O., and Besser, M.J.
Front. Immunol., Vol. 11.
2021

Implementing Logic Gates for Safer Immunotherapy of Cancer

Mohammed Azharuddin Savanur, Hadas Weinstein-Marom, Gideon Gross
Front. Immunol. Nov 4; 12:780399.
2021

The Intracellular Domain of CD40 is a Potent Costimulatory Element in Chimeric Antigen Receptors

Ofir Levin-Piaeda, Noam Levin, Sarah Pozner, Adi Danieli, Hadas Weinstein-Marom, Gideon Gross
J. Immunother., 44, 209-213.
2021

Combined expression of genetic adjuvants exerts multiple immunostimulatory effects on antitumor T cells.

Weinstein-Marom, H., Levin, N., Pato, A., Peretz, T., Eisenberg, G., Lotem, M., Itzhaki, O., Besser, M.J. and Gross, G.
J. Immunother. 42, 43-50. 2019
J. Immunother. 42, 43-50.
2019

MHC-I presentation of distinct antigenic peptides derived from protein products of the pioneer round of translation

Weinstein-Marom, H., Hendel, L., Avigad-Laron, E., Margalit, A. and Gross, G.
FASEB. J. 33, 11458-11468.
FASEB Journal
2019

Potent activation of human T cells by mRNA encoding constitutively active CD40.

Levin, N., Weinstein-Marom, H., Pato, A., Itzhaki, O., Besser, M.J., Peretz, T., Eisenberg, G., Lotem, M. and Gross, G. (2018)
J. Immunology 201, 2959–2968
J. Immunology 201, 2959–2968.
2018

Membrane-attached cytokines expressed by mRNA electroporation act as potent T cell adjuvants.

Weinstein-Marom, H., Pato, A., Levin, N., Susid, K., Itzhaki, O., Besser, M.J., Peretz, T., Margalit, A., Lotem, M. and Gross, G.
J. Immuother. 2016 Volume 39 Pages 60-70
2016

Efficient peptide recovery from secreted recombinant MHC-I molecules expressed via mRNA transfection.

Lazarus, D., Weinstein-Marom, H., Fishman, S., Yossef, Y., Zuri, D,. Barnea, E., Admon, A., Margalit, A. and G. Gross, G.
Immunol. Lett. 2015 Volume 165 Pages 32-38
2015