Vasodilation and blood pressure-lowering effect mediated by 5,6-EEQ lactone in 5/6 nephrectomy hypertensive rats

Barsheshet M, Ertracht O, Boginya A, Reuveni T, Shaul A, Szuchman-Sapir A.
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1866(12):159031
https://www.sciencedirect.com/science/article/abs/pii/S1388198121001591
Researcher
Dr. Andrea Szuchman-Sapir
Description
Highlights
- EPA-L administration to 5/6Nx rats reduced blood pressure.
- EPA-L improves microvascular dilation of 5/6Nx rat mesenteric arteries.
- EPA-L vasodilation is mediated by IKca and SKca endothelial channels.