Computational Chemistry

Latest Publications

Efficient Isothermal Titration Calorimetry Technique Identifies Direct Interaction of Small Molecule Inhibitors with the Target Protein.

Gal, M., Bloch I., Shechter, N., Romanenko, O., Shir, O.M.
Comb Chem High Throughput Screen 2016 Volume 19 Issue 1 Pages 4-13

Specificity in transmembrane helix-helix interactions mediated by aromatic residues

Sal-Man N, Gerber D, Bloch I, Shai Y.
J Biol Chem. 2007

T-Cell inactivation and immunosuppressive activity induced by HIV gp41 via novel interacting motif

Bloch I, Quintana FJ, Gerber D, Cohen T, Cohen IR, Shai Y.
FASEB J. 2006

D-enantiomer peptide of the TCRalpha transmembrane domain inhibits T-cell activation in vitro and in vivo

Gerber D, Quintana FJ, Bloch I, Cohen IR, Shai Y.
FASEB J. 2005 Volume 19 Issue 9 Pages 1190-2

Molecular flexibility in ab initio drug docking to DNA: binding-site and binding-mode transitions in all-atom Monte Carlo simulations

Rohs R, Bloch I, Sklenar H, Shakked Z.
Nucleic Acids Res. 2005 Volume 33 Issue 22 Pages 7048-57