Computational Chemistry

MSc Itai Bloch

Principal Researcher

MSc Itai Bloch

MSc Itai Bloch
Computational Chemistry

As of today the focus of pharmaceutical research is limited to a small fraction of the therapeutic target space. Among the major difficulties dealing with “non-standard” drug targets are:

Latest Publications

Efficient Isothermal Titration Calorimetry Technique Identifies Direct Interaction of Small Molecule Inhibitors with the Target Protein.

Gal, M., Bloch I., Shechter, N., Romanenko, O., Shir, O.M.
Comb Chem High Throughput Screen 2016 Volume 19 Issue 1 Pages 4-13

Specificity in transmembrane helix-helix interactions mediated by aromatic residues

Sal-Man N, Gerber D, Bloch I, Shai Y.
J Biol Chem. 2007

T-Cell inactivation and immunosuppressive activity induced by HIV gp41 via novel interacting motif

Bloch I, Quintana FJ, Gerber D, Cohen T, Cohen IR, Shai Y.
FASEB J. 2006

D-enantiomer peptide of the TCRalpha transmembrane domain inhibits T-cell activation in vitro and in vivo

Gerber D, Quintana FJ, Bloch I, Cohen IR, Shai Y.
FASEB J. 2005 Volume 19 Issue 9 Pages 1190-2

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