Principal Researcher
MSc Itai Bloch
Computational Chemistry
97247700512
As of today the focus of pharmaceutical research is limited to a small fraction of the therapeutic target space. Among the major difficulties dealing with “non-standard” drug targets are:
Latest Publications
Efficient Isothermal Titration Calorimetry Technique Identifies Direct Interaction of Small Molecule Inhibitors with the Target Protein.
Comb Chem High Throughput Screen 2016 Volume 19 Issue 1 Pages 4-13
2016
Specificity in transmembrane helix-helix interactions mediated by aromatic residues
J Biol Chem. 2007
2007
T-Cell inactivation and immunosuppressive activity induced by HIV gp41 via novel interacting motif
FASEB J. 2006
2006
Molecular flexibility in ab initio drug docking to DNA: binding-site and binding-mode transitions in all-atom Monte Carlo simulations
Nucleic Acids Res. 2005 Volume 33 Issue 22 Pages 7048-57
2005