Virology and Poultry Vaccination

Prof. Jacob Pitcovski

Endotoxin-free gram-negative bacterium as a system for production and secretion of recombinant proteins.

Shahar E, Emquies K, Bloch I, Eliahu D, Ben Adiva R, Pitcovski J, Yadid I.
Appl Microbiol Biotechnol. 2023 Jan;107(1):287-298. doi: 10.1007/s00253-022-12295-1. Epub 2022 Nov 29.
PMID: 36445389
2023

Oral subunit SARS-CoV-2 vaccine induces systemic neutralizing IgG, IgA and cellular immune responses and can boost neutralizing antibody responses primed by an injected vaccine.

Pitcovski J, Gruzdev N, Abzach A, Katz C, Ben-Adiva R, Brand-Shwartz M, Yadid I, Ratzon-Ashkenazi E, Emquies K, Israeli H, Haviv H, Rapoport I, Bloch I, Shadmon R, Eitan Z, Eliahu D, Hilel T, Laster M, Kremer-Tal S, Byk-Tennenbaum T, Shahar E.
Vaccine. 2022 Feb 16;40(8):1098-1107. doi: 10.1016/j.vaccine.2022.01.025. Epub 2022 Jan 19.
PMID: 35078662 Free PMC article.
2022

Protection against avian coronavirus conferred by oral vaccination with live bacteria secreting LTB-fused viral proteins.

Lublin A, Katz C, Gruzdev N, Yadid I, Bloch I, Farnoushi Y, Simanov L, Berkowitz A, Elyahu D, Pitcovski J, Shahar E.

Vaccine. 2022 Jan 31;40(5):726-733. doi: 10.1016/j.vaccine.2021.12.053. Epub 2021 Dec 30.
PMID: 34998606 Free PMC article.
2022

Newcastle disease virus: is an updated attenuated vaccine needed?

Shahar E, Haddas R, Goldenberg D, Lublin A, Bloch I, Bachner Hinenzon N, Pitcovski J.
Avian Pathol. 2018 Oct;47(5):467-478. doi: 10.1080/03079457.2018.1488240. Epub 2018 Jul 5.
PMID: 29897786
2018

Immune modulation and treatment of Human papilloma virus-related warts by energetics of living systems acupuncture

Brustin, R., Toledano, M, Geffen, T., Goona, R., Hochberg , m., Kreisberg, B., Murad, S., and Pitcovski, J.
Medical acupuncture 2017 Volume 29 Pages 145-154
2017

Pair-epitopes vaccination: enabling offspring vaccination in the presence of maternal antibodies

Pitcovski, J., Pitcovski, E., Goldenberg, d., and Shahar, E.
Avian Pathology 2017 Volume Accepted
2017

Review: Melanoma antigens and related immunological markers

Pitcovski, J., Shahar, E., Aizenshtein, E. and Gorodetsky, R.
Critical Reviews in Oncology/Hematology 2017 Volume 115 Pages 36-49
2017

Variation among replicates can influence repeatability

Jacob Pitcovski, Ehud Shahar and Avigdor Cahaner
In Stepping in the Same River Twice: Replication in Biological Research ,2017, Ayelet Shavit and Aaron M. Ellison Ed. ,Yale University Press , Pages
2017

Formation of multimeric antibodies for self-delivery of active monomers

Dekel Y, Machluf Y, Gefen T, Eidelshtein G, A Kotlyar, Bram Y, Shahar E, Reslane F, Aizenshtein E and Pitcovski J.
Drug Delivery 2017 Volume 24 Issue 1 Pages 199-208
2017

Practical aspects in the use of passive immunization as an alternative to attenuated viral vaccines.

Aizenshtein, E., Yosipovich, R, Kvint, M, Shadmon, R, Krispel, S, Shuster, E, Finger, A, Banet-Noach, C, Shahar, E and Jacob Pitcovski
Vaccine 2016 Volume 34 Pages 2513?2518
2016

Optimized polypeptide for a subunit vaccine against avian reovirus.

Goldenberg D, Lublin A, Rosenbluth E, Heller E.D, Pitcovski J.
Vaccine 2016 Volume 34 Pages 3178-3183
2016

Immunological complex for enhancement of innate immune response in passive vaccination

E. Aizenshtein; Y. Pinchasov; E. Morag; G. Leitner; Y. Shpanir; D. Reimond; J. Pitcovski
Vaccine 2013 Volume 31 Issue 4 Pages 626-631
2013

Immunotherapy of mastitis

G. Leitner; Y. Pinchasov; E. Morag; Y. Spanier; S. Jacoby; D. Eliau; J. Pitcovski
Veterinary Immunology and Immunopathology 2013 Volume 153 Pages 209-216
2013

The impact of PEGylation on protein immunogenicity

T. Gefen; J. Vaya; S. Khatib; N. Harkevich; F. Artoul; E. D. Heller; J. Pitcovski; E. Aizenshtein
International Immunopharmacology 2013 Volume 15 Issue 2 Pages 254-259
2013

Immune responses to mucosal vaccination by the recombinant S1 and N proteins of infectious bronchitis virus

R. Meir; S. Krispel; L. Simanov; D. Eliahu; O. Maharat; J. Pitcovski
Viral Immunology 2012 Volume 25 Issue 1 Pages 55-62
2012

Differentiating infected from vaccinated animals, and among virulent prototypes of reovirus

D. Goldenberg; A. Lublin; E. Rosenbluth; E. D. Heller; J. Pitcovski
Journal of Virological Methods 2011 Volume 177 Issue 1 Pages 80-86
2011

Wide-range protection against avian reovirus conferred by vaccination with representatives of four defined genotypes

A. Lublin; D. Goldenberg; E. Rosenbluth; E. D. Heller; J. Pitcovski
Vaccine 2011 Volume 29 Issue 47 Pages 8683-8688
2011

Genetic and antigenic characterization of sigma C protein from avian reovirus

D. Goldenberg; M. Pasmanik-Chor; M. Pirak; N. Kass; A. Lublin; A. Yeheskel; D. Heller; J. Pitcovski
Avian Pathology 2010 Volume 39 Issue 3 Pages 189-199
2010

Targeted microbeads for attraction and induction of specific innate immune response in the tumor microenvironment

E. Shahar; R. Gorodetsky; E. Gaberman; E. Aizenshtein; J. Pitcovski
Vaccine 2010 Volume 28 Issue 45 Pages 7279-7287
2010

Transcutaneous immunization with hydrophilic recombinant gp100 protein induces antigen-specific cellular immune response

G. Eisenberg; A. Machlenkin; S. Frankenburg; A. Mansura; J. Pitcovski; E. Yefenof; T. Peretz; M. Lotem
Cellular Immunology 2010 Volume 266 Issue 1 Pages 98-103
2010

Adsoption of two vaccine-related proteins to montmorillonite and organo-montmorillonite

G. Rytwo; A. Mendelovits; D. Eliyahu; J. Pitcovski; E. Aizenshtein
Applied Clay Science 2010 Volume 50 Issue 4 Pages 569-575
2010

Coated cross-species antibodies by mannosamine-biotin adduct confer protection against snake venom without eliciting humoral immune response

T. Gefen; J. Pitcovski; J. Vaya; S. Khatib; S. Krispel; E. D. Heller; E. Gaberman; R. Gorodetsky; E. Aizenshtein
Vaccine 2010 Volume 28 Issue 51 Pages 8197-8202
2010

Mannosamine-biotin as a novel masking agent for coating IgG for immune response silencing and augmentation of antibody-antigen interaction

J. Vaya; E. Aizenshtein; S. Khatib; T. Gefen; M. Fassler; R. Musa; S. Krispel; J. Pitcovski
Vaccine 2009 Volume 27 Issue 49 Pages 6869-6876
2009

Capture of tumor cell membranes by trogocytosis facilitates detection and isolation of tumor-specific functional CTLs

A. Machlenkin; R. Uzana; S. Frankenburg; G. Eisenberg; L. Eisenbach; J. Pitcovski; R. Gorodetsky; A. Nissan; T. Peretz; M. Lotem
Cancer Research 2008 Volume 68 Issue 6 Pages 2006-2013
2008

Recombinant egg drop syndrome subunit vaccine offers an alternative to virus propagation in duck eggs

B. Gutter; E. Fingerut; G. Gallili; D. Eliahu; B. Perelman; A. Finger; J. Pitcovski
Avian Pathology 2008 Volume 37 Issue 1 Pages 33-37
2008