Natural Products and Analytical Chemistry

Prof. Soliman Khatib

Reduced glutathione (GSH) increases quercetin stimulatory effects on HDL- or apoA1- mediated cholesterol efflux from J774A.1 macrophages

Rosenblat M, Volkova N, Khatib S, Mahmood S, Vaya J, Aviram M.
Free Radic Res 2014 Volume 48 Issue 12 Pages 1462-1472
2014

Analysis of volatile organic compounds in rats with dopaminergic lesion: possible application for early detection of Parkinson?s disease

S. Khatib, J.P.M. Finberg, F. Artoul, Y. Lavner, S. Mahmood, U. Tisch, H. Haick, Y. Aluf, J. Vaya
Neurochemistry International 2014 Volume 76 Pages 82-90
2014

Selective inhibition of monoamine oxidase A or B reduces striatal oxidative stress in rats with partial depletion of the nigro-striatal dopaminergic pathway

Y. Aluf; J. Vaya; S. Khatib; Y. Loboda; J. P. M. Finberg
Neuropharmacology 2013 Volume 65 Pages 48-57
2013

The effects and mechanism of flavonoid-rePON1 interactions. Structure-activity relationship study

D. Atrahimovich; J. Vaya; S. Khatib
Bioorganic and Medicinal Chemistry 2013 Volume 21 Issue 11 Pages 3348-3355
2013

The impact of PEGylation on protein immunogenicity

T. Gefen; J. Vaya; S. Khatib; N. Harkevich; F. Artoul; E. D. Heller; J. Pitcovski; E. Aizenshtein
International Immunopharmacology 2013 Volume 15 Issue 2 Pages 254-259
2013

Glabridin protects paraoxonase 1 from linoleic acid hydroperoxide inhibition via specific interaction: A fluorescence-quenching study

D. Atrahimovich; J. Vaya; H. Tavori; S. Khatib
Journal of Agricultural and Food Chemistry 2012 Volume 60 Issue 14 Pages 3679-3685
2012

Increased levels of human carotid lesion linoleic acid hydroperoxide in symptomatic and asymptomatic patients, is inversely correlated with serum HDL and paraoxonase 1 activity.

E. Cohen, M. Aviram, S. Khatib, A. Rabin, D. Mannheim, R. Karmeli, J. Vaya.
Journal of Lipids 2012 Volume 2012 Pages Article ID 762560
2012

Paraoxonase1 deficiency in mice is associated with hypotension and increased levels of 5,6-epoxyeicosatrienoic acid

A. Gamliel-Lazarovich; Z. Abassi; S. Khatib; H. Tavori; J. Vaya; M. Aviram; S. Keidar
Atherosclerosis 2012 Volume 222 Issue 1 Pages 92-98
2012

Human carotid lesion linoleic acid hydroperoxide inhibits paraoxonase 1 (PON1) activity via reaction with PON1 free sulfhydryl cysteine 284

H. Tavori; M. Aviram; S. Khatib; R. Musa; D. Mannheim; R. Karmeli; J. Vaya
Free Radical Biology and Medicine 2011 Volume 50 Issue 1 Pages 148-156
2011

Paraoxonase 1 protects macrophages from atherogenicity of a specific triglyceride isolated from human carotid lesion

H. Tavori; M. Aviram; S. Khatib; R. Musa; D. Mannheim; R. Karmeli; J. Vaya
Free Radical Biology and Medicine 2011 Volume 51 Issue 1 Pages 234-242
2011

Structure activity relationships of flavonoids

Vaya Jacob, Tavori Hagai, Khatib Soliman.
Current Organic Chemistry 2011 Volume 15(15) Pages 2641-2657
2011

Alterations in striatal oxidative stress level produced by pharmacological manipulation of dopamine as shown by a novel synthetic marker molecule

Y. Aluf; J. Vaya; S. Khatib; J. P. M. Finberg
Neuropharmacology 2011 Volume 61 Pages 87-94
2011

Fig, carob, pistachio, and health

S. Khatib; J. Vaya
In ,2010, Ed. ,Elsevier Inc. , Pages 245-263
2010

Specific oxidative stress profile associated with partial striatal dopaminergic depletion by 6-hydroxydopamine as assessed by a novel multifunctional marker molecule

Y. Aluf; J. Vaya; S. Khatib; Y. Loboda; S. Kizhner; J. P. M. Finberg
Free Radical Research 2010 Volume 44 Issue 6 Pages 635-644
2010

Coated cross-species antibodies by mannosamine-biotin adduct confer protection against snake venom without eliciting humoral immune response

T. Gefen; J. Pitcovski; J. Vaya; S. Khatib; S. Krispel; E. D. Heller; E. Gaberman; R. Gorodetsky; E. Aizenshtein
Vaccine 2010 Volume 28 Issue 51 Pages 8197-8202
2010

Differential stress responses among newly received calves: Variations in reductant capacity and Hsp gene expression

H. Eitam; J. Vaya; A. Brosh; A. Orlov; S. Khatib; I. Izhaki; A. Shabtay
Cell Stress and Chaperones 2010 Volume 15 Issue 6 Pages 865-876
2010

Potential skin antiinflammatory effects of 4-methylthiobutylisothiocyanate (MTBI) isolated from rocket (Eruca sativa) seeds

H. Yehuda; S. Khatib; I. Sussan; R. Musa; J. Vaya; S. Tamir
BioFactors 2009 Volume 35 Issue 3 Pages 295-305
2009

Brain sterol dysregulation in sporadic AD and MCI: Relationship to heme oxygenase-1

J. R. Hascalovici; J. Vaya; S. Khatib; C. A. Holcroft; H. Zukor; W. Song; Z. Arvanitakis; D. A. Bennett; H. M. Schipper
Journal of Neurochemistry 2009 Volume 110 Issue 4 Pages 1241-1253
2009

Impact of heme oxygenase-1 on cholesterol synthesis, cholesterol efflux and oxysterol formation in cultured astroglia

J. R. Hascalovici; W. Song; J. Vaya; S. Khatib; B. Fuhrman; M. Aviram; H. M. Schipper
Journal of Neurochemistry 2009 Volume 108 Issue 1 Pages 72-81
2009

Characterization of the PON1 active site using modeling simulation, in relation to PON1 lactonase activity

H. Tavori; S. Khatib; M. Aviram; J. Vaya
Bioorganic and Medicinal Chemistry 2008 Volume 16 Issue 15 Pages 7504-7509
2008

Enhanced substituted resorcinol hydrophobicity augments tyrosinase inhibition potency

S. Khatib; O. Nerya; R. Musa; S. Tamir; T. Peter; J. Vaya
Journal of Medicinal Chemistry 2007 Volume 50 Issue 11 Pages 2676-2681
2007

An exogenous marker: A novel approach for the characterization of oxidative stress

S. Khatib; R. Musa; J. Vaya
Bioorganic and Medicinal Chemistry 2007 Volume 15 Issue 11 Pages 3661-3666
2007

Characterization of oxidative stress in blood from diabetic versus hypercholesterolemic patients, using a novel synthesized marker

Szuchman A, Aviram M, Musa R, Soliman K, Vaya J.
Biomarkers 2007 Volume 30 Pages 1-13
2007

Effects of heme oxygenase-1 expression on sterol homeostasis in rat astroglia

J. Vaya; W. Song; S. Khatib; G. Geng; H. M. Schipper
Free Radical Biology and Medicine 2007 Volume 42 Issue 6 Pages 864-871
2007

Exogenous N-linoleoyl tyrosine marker as a tool for the characterization of cellular oxidative stress in macrophages

A. Szuchman; M. Aviram; K. Soliman; S. Tamir; J. Vaya
Free Radical Research 2006 Volume 40 Issue 1 Pages 41-52
2006