Immunology

Prof. Gideon Gross

Developing a novel model system to target insulin reactive CD8 T cells

Scott, G. S., Fishman, S., Margalit, A., Siew L. K., Chapman, S., Wen, L., Gross, G. & Wong, F. S.
Ann. N.Y. Acad. Sci. 2008 Volume 1150, Pages 54?58
2008

Targeting tumor-associated antigens to the MHC class I presentation pathway

G. Gross; A. Margalit
Endocrine, Metabolic and Immune Disorders - Drug Targets 2007 Volume 7 Issue 2 Pages 99-109
2007

Induction of anti-tumor immunity by CTL epitopes genetically linked to membrane- anchored beta2 microglobulin

Margalit, A., Migalovich Sheikhet, H., Carmi, Y., Berko, D., Tzehoval, E., Eisenbach, L. & Gross, G.
J. Immunol. 2006 Volume 176 Pages 217-224
2006

HIV-1 neutralization by chimeric CD4-CG10 polypeptides fused to human IgG1

R. Meyuhas; H. Noy; D. C. Montefiori; G. Denisova; J. M. Gershoni; G. Gross
Molecular Immunology 2005 Volume 42 Issue 9 Pages 1099-1109
2005

Membrane-anchored β2-microglobulin stabilizes a highly receptive state of MHC class I molecules

D. Berko; Y. Carmi; G. Cafri; S. Ben-Zaken; H. M. Sheikhet; E. Tzehoval; L. Eisenbach; A. Margalit; G. Gross
Journal of Immunology 2005 Volume 174 Issue 4 Pages 2116-2123
2005

The mapping and reconstitution of a conformational discontinuous B-cell epitope of HIV-1

D. Enshell-Seijffers; D. Denisov; B. Groisman; L. Smelyanski; R. Meyuhas; G. Gross; G. Denisova; J. M. Gershoni
Journal of Molecular Biology 2003 Volume 334 Issue 1 Pages 87-101
2003

Chimeric ?2 microglobulin/CD3?polypeptides expressed in T cells convert MHC class I peptide ligands into T cell activation receptors: a potential tool for specific targeting of pathogenic CD8+ T cells

A. Margalit; S. Fishman; D. Berko; J. Engberg; G. Gross
International Immunology 2003 Volume 15 Issue 11 Pages 1379-1387
2003

Development and large-scale use of recombinant VP2 vaccine for the prevention of infectious bursal disease of chickens

J. Pitcovski; B. Gutter; G. Gallili; M. Goldway; B. Perelman; G. Gross; S. Krispel; M. Barbakov; A. Michael
Vaccine 2003 Volume 21 Issue 32 Pages 4736-4743
2003

In-cell generation of antibody single-chain Fv transcripts by targeted RNA trans-splicing

J. Schlesinger; D. Arama; H. Noy; M. Dagash; P. Belinky; G. Gross
Journal of Immunological Methods 2003 Volume 282 Pages 175-186
2003

Antibody expression from the core region of the human IgH locus reconstructed in transgenic mice using bacteriophage P1 clones

S. D. Wagner; G. Gross; G. P. Cook; S. L. Davies; M. S. Neuberger
Genomics 1996 Volume 35 Issue 3 Pages 405-414
1996

The T-body approach: Potential for cancer immunotherapy

Z. Eshhar; N. Bach; C. J. Fitzer-Attas; G. Gross; J. Lustgarten; T. Waks; D. G. Schindler
Springer Seminars in Immunopathology 1996 Volume 18 Issue 2 Pages 199-209
1996

T-bodies: Chimeric T-cell receptors with antibody-type specificity

Z. Eshhar; G. Gross; T. Waks; J. Lustgarten; N. Bach; A. Ratner; J. Treisman; D. G. Schindler
Methods: A Companion to Methods in Enzymology 1995 Volume 8 Issue 2 Pages 133-142
1995

Chimaeric T-cell receptors specific to a B-lymphoma idiotype: A model for tumour immunotherapy

G. Gross; S. Levy; R. Levy; T. Waks; Z. Eshhar
Biochemical Society Transactions 1995 Volume 23 Issue 4 Pages 1079-1082
1995

Anti-leucocyte function-associated antigen-1 antibodies inhibit T-cell activation following low-avidity and adhesion-independent interactions

G. Gorochov; G. Gross; T. Waks; Z. Eshhar
Immunology 1993 Volume 79 Issue 4 Pages 548-555
1993

Lysis of ovarian cancer cells by human lymphocytes redirected with a chimeric gene composed of an antibody variable region and the Fc receptor γ chain

P. Hwu; G. E. Shafer; J. Treisman; D. G. Schindler; G. Gross; R. Cowherd; S. A. Rosenberg; Z. Eshhar
Journal of Experimental Medicine 1993 Volume 178 Issue 1 Pages 361-366
1993

Modifying the specificity of T cells using chimeric Ig/TCR genes.

Eshhar, Z., Gross G. & Treisman J
In Tumour Immunobiology: A Practical Approach ,1993, G. Gallagher, R. C. Rees & C. W. Reynolds, Ed. ,Oxford University Press , Pages 345-368.
1993

Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the γ or ζ subunits of the immunoglobulin and T-cell receptors

Z. Eshhar; T. Waks; G. Gross; D. G. Schindler
Proceedings of the National Academy of Sciences of the United States of America 1993 Volume 90 Issue 2 Pages 720-724
1993

Endowing T cells with antibody specificity using chimeric T cell receptors

G. Gross; Z. Eshhar
FASEB Journal 1992 Volume 6 Issue 15 Pages 3370-3378
1992

Functional assembly of chimeric T-cell receptor chains

G. Gorochov; J. Lustgarten; T. Waks; G. Gross; Z. Eshhar
International Journal of Cancer 1992 Issue SUPPL. 7 Pages 53-57
1992

Chimeric T cell receptor which incorporates the anti-tumour specificity of a monoclonal antibody with the cytolytic activity of T cells: a model system for immunotherapeutical approach

Z. Eshhar; G. Gross
The British journal of cancer. Supplement 1990 Volume 10 Pages 27-29
1990

Expression of chimeric antibody/T cell receptor genes as functional receptor molecules in human and mouse T cells.

Gorochov, G., Gross, G., Waks, T. & Eshhar, Z.
Wiley-Liss Inc. New York, N.Y. ,1990
1990

Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity

G. Gross; T. Waks; Z. Eshhar
Proceedings of the National Academy of Sciences of the United States of America 1989 Volume 86 Issue 24 Pages 10024-10028
1989

Functional expression of a chimeric T cell receptor with an antibody binding site.

Gross, G., Waks, T. & Eshhar, Z.
Alan R. Liss Inc. New York, USA ,1989
1989

Generation of effector T cells expressing chimeric T cell receptor with antibody type-specificity

G. Gross; G. Gorochov; T. Waks; Z. Eshhar
Transplantation Proceedings 1989 Volume 21 Issue 1 I Pages 127-130
1989

Promoter and enhancer elements in the rearranged alpha chain gene of the human T cell receptor

S. Luria; G. Gross; M. Horowitz; D. Givol
EMBO Journal 1987 Volume 6 Issue 11 Pages 3307-3312
1987