Dr. Itamar Yadid

Dr. Itamar Yadid
Research Group Leader

Bacteria can rapidly adapt to the constantly changing environment by the acquisition and evolution of new metabolic pathways. Research in the lab is aimed at understanding and characterizing this outstanding ability at the molecular level. We would like to apply the acquired knowledge to various fields, from understanding the complex interactions between a pathogen and its host to the engineering of microorganisms for the production of renewable energy. We use knowledge and methods from the fields of microbiology, biochemistry, protein engineering and evolution to understand the processes and to apply them in the most efficient and environmental friendly way.


Ph.D. 2009, The Weizmann Institute of Science, Israel,
M.Sc. 2004, The Weizmann Institute of Science, Israel

Academic positions
2013- Head of Molecular and Environmental Microbiology Laboratory, MIGAL– Galilee Research institute.
2010-2013 Post-doctoral Research fellow, lab of Prof. Shelley D. Copley at the University of Colorado at Boulder

Scientific Publications

Directed evolution of an endoinulinase from Talaromyces purpureogenus toward efficient production of inulooligosaccharides.

Afriat-Jurnou L, Cohen R, Paluy I, Ben-Adiva R, Yadid I.
Biotechnol Prog. 2018 Volume Jul;34 Issue 4 Pages 868-877

Olive Mill Waste Enhances ?-Glucan Content in the Edible Mushroom Pleurotus eryngii

Avni S, Ezove N, Hanani H, Yadid I, Karpovsky M, Hayby H, Gover O, Hadar Y, Schwartz B, Danay O.
Int J Mol Sci 2017 Volume 18 Issue 7 Pages 1564

De Novo Evolutionary Emergence of a Symmetrical Protein Is Shaped by Folding Constraints

Robert G. Smock, Itamar Yadid, Orly Dym, Jane Clarke, Dan S. Tawfik
Cell 2016 Volume 164 Issue 3 Pages 476?486

A novel microfluidic rapid freeze-quench device for trapping reactions intermediates for high field EPR analysis

R. Kaufmann; I. Yadid; D. Goldfarb
J Magn Reson 2013 Volume 230 Pages 220-6

Sequestration of a highly reactive intermediate in an evolving pathway for degradation of pentachlorophenol

I. Yadid; J. Rudolph; K. Hlouchova; S. D. Copley
Proc Natl Acad Sci U S A 2013 Volume 110 Issue 24 Pages E2182-90

Functional beta-propeller lectins by tandem duplications of repetitive units

I. Yadid; D. S. Tawfik
Protein Eng Des Sel 2011 Volume 24 Issue 01-??? Pages 185-95

Metamorphic proteins mediate evolutionary transitions of structure

I. Yadid; N. Kirshenbaum; M. Sharon; O. Dym; D. S. Tawfik
Proc Natl Acad Sci U S A 2010 Volume 107 Issue 16 Pages 7287-92

Reconstruction of functional beta-propeller lectins via homo-oligomeric assembly of shorter fragments

I. Yadid; D. S. Tawfik
J Mol Biol 2007 Volume 365 Issue 1 Pages 06-???