Principal Researcher
Dr. Dorit Avni
Immune Modulation & Natural Biocompounds
054-9815556
We strive to understand the mechanisms of inflammation and cancer that underlie the involvement of sphingolipids and to translate these laboratory discoveries into new therapies
Latest Publications
p70S6K as a Potential Anti-COVID-19 Target: Insights from Wet Bench and In Silico Studies
Cells 13(21)
2024
Sphingosine-1-phosphate phosphatase 2 promotes disruption of mucosal integrity, and contributes to ulcerative colitis in mice and humans. FASEB J
2016
Exogenous ceramide-1-phosphate (C1P) and phospho-ceramide analogue-1 (PCERA-1) regulate key macrophage activities via distinct receptors. Immunol Lett
2016
The phosphorylated prodrug FTY720 is a histone deacetylase inhibitor that reactivates ERα expression and enhances hormonal therapy for breast cancer. Oncogenesis
2015