Dr. Idan Pereman

Dr. Idan Pereman
Principal Investigator
Phone
972-4-6953511

Lab Website

Medicinal Mushrooms Lab
Quote
" a chicken is only an egg's way of making another egg" Umberto Eco

First of all - we love mushrooms! 

Then we focus on ways in which mushrooms can support our health, our nutrition and the betterment of the environment and the world around us. 

Our research strategy goes bottom up:

We grow a kaleidoscop of different mushrooms in controlled cultivation facilities  followed by cutting-edge molecular and analytical chemistry methods in order to look into the mushroom's "black box".

We then subject the mushroom extractions to bioactivity tests using advanced models of cell lines and whole organisms.

Through this unique approach, linking bioactivity to gene expression and metabolomics, we expect to discover novel and natural treatments to well- known chronic diseases with little current remedy.

 

In addition our group is determined to promote mushrooms' mycelium as an excellent (and super tasty) source of protein, replacing meat consumption by half (in collaboration with "Mushfoods" company).

The more romantic part of our group is dedicated to strolling among trees studying mycorrhizal interactions in orchards and  forests, specifically studying the life cycle of local black truffles (Tuber aestivum and Tuber melanosporum) with the aim of making them accessible in local markets. 

 

 

CV

 

Education:

2008-2013    Ph.D in Biology (Dean’s scholarship for outstanding students) - Molecular Biology and Ecology of Plants Department- Tel-Aviv University-Israel.

Doctoral Dissertation: The Role of the Polycomb Complex in H3K27 Methylation and Phase Transition in Physcomitrella patens.

2003-2005    M.Sc in Biology (With Distinction) - Cell Research and Immunology Department - Tel-Aviv University-Israel.

Master's Thesis: Characterization of the Poly(A) - Binding Protein (PABP) during the cell cycle.

2000-2002    B.Sc. in Biology (With Distinction) - Tel-Aviv University-Israel.

 

Advanced studies:

2014-2018 Post-Doctoral studies - Weizmann institute of science Rehovot-Israel

Cryo-Scanning-Transmission-Electron-Microscopy (Cryo-STEM) imaging of chromatin in yeast nuclei. Chemical and biological physics Department (2016-2018)  .

Live imaging and tracking of Agrobacterium tumefaciens T-DNA dynamics in Nicotiana benthamiana. Plant and environmental sciences department (2014-2016)    .

Scientific Publications

Unveiling the Chemical Composition and Biofunctionality of Hericium spp. Fungi: A Comprehensive Overview.

Elizabeth Kostanda, Sanaa Musa and Idan Pereman.
2024

Olive mill solid waste induces beneficial mushroom-specialized metabolite diversity: a computational metabolomics study.

Soliman Khatib, Idan Pereman, Elizabeth Kostanda, Mitja M. Zdouc, Nirit Ezov, Ron Schweitzer, and Justin J. J. van der Hooft.
2024

Compounds originating from the edible mushroom Auricularia auricula-judae inhibit tropomyosin receptor kinase B activity.

Orr Shahar, Idan Pereman, Hazem Khamaisi, Nirit Ezov, Ofir Degani, Ali Khatib, Ron Schweitzer, Soliman Khatib, Jamal Mahajna.
2022

Ochodaeus berytensis Petrovitz (Coleoptera: Ochodaeidae), a new pest of the truffle Tuber aestivum in Upper Galilee, Israel.

Jean-Bernard Huchet, Lotem Azoulay, Ofer Danay, Nirit Ezov, Idan Pereman, Ariel-Leib Friedman, Liora Shaltiel-Harpaz
2022

Single Molecule Imaging of T-DNA Intermediates Following Agrobacterium tumefaciens Infection in Nicotiana benthamiana

Idan Pereman, Cathy Bessudo, Tal Dahan-Meir
International Journal of Molecular Sciences (IJMS) 20(24):6209
DOI:10.3390/ijms20246209
2019

Direct fluorescence detection of VirE2 secretion by Agrobacterium tumefaciens

Noga Yaakov, Yoav Barak, Idan Pereman, Peter J. Christie
2017

A single homeobox gene triggers phase transition, embryogenesis and asexual reproduction

Nelly A Horst, Aviva Katz, Idan Pereman, Eva L Decker
Nature Plants 2(2):15209
2016

The Polycomb group protein CLF emerges as a specific tri-methylase of H3K27 regulating gene expression and development in Physcomitrella patens

Idan Pereman, Assaf Mosquna, Aviva Katz, Gertrud Wiedemann
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1859
2016