The laboratory of organic synthesis, analytical and medicinal chemistry

Applied scientific research, specializing in the fields of biotechnology, environmental and agriculture sciences

Dr. Sanaa Musa

Title
Our research group specializes in the design and synthesis of hybrid molecules as promising candidates for novel drug development.

 

Specifically, our ongoing research area includes: 

  1. Development of nitric oxide (NO) and hydrogen sulfide (H2S) hybrid donor compounds based on cannabinoid scaffold and exploring their dual activity in cardiovascular- and neurodegenerative-related diseases. 
  2. Development of Schiff bases-cannabinoid hybrid compounds and evaluation of their biological activity on the melanogenesis process.
  3. Development of Platinum-hybrid complexes, with a particular focus on their potential as anti-cancer drugs. (in collaboration with Prof. Jamal Mahajna)

Additionally, we are focusing on microencapsulation technology to encapsulate bioactive compounds. We investigate their stability and controlled release, aiming to extend the shelf life of a diverse range of food products.

Our group members:
Yuval Peretz, Lab manager
Eliav Peretz, Master student
Noor Amara, Master student
Gil Dinnar, Research Assistant

 

Principal Researcher

Latest Publications

Unveiling the chemical composition and health-promoting activities of Hericium spp. Fungi: A Comprehensive Overview.

Kostanda, E; Musa, S. and Pereman, I. (2024)
Int. J. Mol. Sci. 2024, 25, 5949.
2024

PON1 has palmitoyl-protein thioesterase (PPT) activity, and can affect the presence of SR-B1 on the endothelial cell membrane.

Ashkar, R.; Khattib, A.; Musa, S.; Goldberg, D. and Khatib, S.
BioFactors.
2023

Dehydrogenative Cross-Coupling of Primary and Secondary Alcohols

Musa, S.; Ackermann, L. and Gelman. D (2013)
Adv. Synth. Catal. 355: 3077–3080. (IF 5.981, Q1)
2023

Eastern Fire Salamander (Salamandra infraimmaculata) Skin Mucus Metabolites – LC-MS/MS Analysis

Degani, G.; Ish-Am G.; Yatom N.; Khatib, S. and Musa, S.
Environ Anal Eco stud., 000747, 10(5).
2023

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