Dr. Ari Meerson

A picture of Dr. Ari Meerson on a visit to a museum in Stockholm
Genomics branch, Head
Research Group Leader
PhD
Phone
972-54-6320771
972-4-6955014
Full CV (PDF)
microRNA; RNA; obesity; diabetes; cancer; gene expression; genomics
Research Interests:

The Meerson group studies the molecular and genomic basis of chronic diseases, with a special focus on the function of microRNAs, short RNA molecules that regulate gene expression and are involved in a variety of biological pathways.  Specifically, we are interested in:

1. MicroRNAs as a mechanistic link between metabolic disease, cancer, and other chronic diseases

2. Discovery of microRNA-based biomarkers of disease in body fluids

3. Transcriptomics of reproduction and development in vertebrates

4. Novel applications of Oxford Nanopore sequencing technology

 

CV

Education and Research:

2013-pres    MIGAL Galilee Research Institute, Kiryat Shmona, Israel. Head of Genomics lab.

2015-2022   University of Copenhagen, Denmark. Guest Researcher, BMI.

2009-2013   NIH/NIDDK (Phoenix), AZ, USA. Postdoctoral Fellow. 

2003-2008   Hebrew University, Jerusalem, Israel.  PhD program, Department of Biological Chemistry. PhD, 2009.

2001-2003   Feinberg Graduate School of the Weizmann Institute of Science, Rehovot, Israel. MSc program, Department of Molecular Cell Biology. MSc, 2004.

1999-2001   Hebrew University, Jerusalem, Israel. Faculty of Life Sciences. Honors Program. BSc 2002, cum laude, completed in 2 years; Dean’s list and scholarship.

 

Assay development:

2017-2021        Developed a qPCR-based genetic assay for establishing the sex of Russian sturgeon fish, for caviar aquaculture. The method is in commercial use by Caviar Galilee ltd. since 2021.

2017                 Developed a qRTPCR-based molecular assay for assessing maize late wilt disease (published)

 

Teaching and Mentoring:

2017-pres    Mentor to 1 PhD student, 4 MSc students, and 9 undergraduate students)

2017-pres    Tel Hai Academic College, Biotechnology Department. Teaching 6 courses: Developmental Genetics (starting 2017); microRNAs/RNA World (starting 2020); Evolution, and Molecular Genetics B (both starting 2021); Practical Workshop in Genomic Lab Methods, and Big Questions in the Life Sciences (both starting 2023). Approved for promotion to Senior Lecturer.

2018-pres    Tel Hai, Science Faculty. Supervisory committee member for 3 MSc students

2016-pres    Tel Hai, Excellence Center. Mentored 8 high school students

Scientific Publications

Altered aPKC signaling contributes to glioblastoma cell migration

Kusne Y, Meerson A, Rushing EJ, Yang W, Aldape K, McDonough W, Kislin K, Loftus JC, Berens M, Lu Z, and Ghosh S
Neuro-Oncology 2010 Volume 12 Issue 15
2010

Changes in brain MicroRNAs contribute to cholinergic stress reactions

A. Meerson; L. Cacheaux; K. A. Goosens; R. M. Sapolsky; H. Soreq; D. Kaufer
Journal of Molecular Neuroscience 2010 Volume 40 Issue 01-??? Pages 47-55
2010

MicroRNA-132 Potentiates Cholinergic Anti-Inflammatory Signaling by Targeting Acetylcholinesterase

I. Shaked; A. Meerson; Y. Wolf; R. Avni; D. Greenberg; A. Gilboa-Geffen; H. Soreq
Immunity 2009 Volume 31 Issue 6 Pages 965-973
2009

MicroRNA-132 regulates brain to body anti-inflammatory signaling

Soreq H, Shaked I, Meerson A, Avni R, Greenberg D, Gilboa-Geffen A
J Neurochem 2009 Volume 110 Pages 15-15
2009

Regulation of Alternative Splicing by Psychological Stress

Flores L, Meerson A, Goosens KA, Sapolsky R, Soreq H, Kaufer D
Society For Neuroscience 2007 Annual Meeting
2007

MicroRNA modulation of megakaryoblast fate involves cholinergic signaling

C. Guimaraes-Sternberg; A. Meerson; I. Shaked; H. Soreq
Leukemia Research 2006 Volume 30 Issue 5 Pages 583-595
2006

Modulation of N-ethylmaleimide-sensitive factor activity upon amino acid deprivation

H. Shorer; N. Amar; A. Meerson; Z. Elazar
Journal of Biological Chemistry 2005 Volume 280 Issue 16 Pages 16219-16226
2005

p53 mediates density-dependent growth arrest

A. Meerson; M. Milyavsky; V. Rotter
FEBS Letters 2004 Volume 559 Issue 02-??? Pages 152-158
2004

Prolonged Culture of Telomerase-Immortalized Human Fibroblasts Leads to a Premalignant Phenotype

M. Milyavsky; I. Shats; N. Erez; X. Tang; S. Senderovich; A. Meerson; Y. Tabach; N. Goldfinger; D. Ginsberg; C. C. Harris; V. Rotter
Cancer Research 2003 Volume 63 Issue 21 Pages 7147-7157
2003