Enzymes Evolution and Environmental and Applied Microbiology
- Enzymes Evolution and Environmental and Applied Microbiology
- Enzymes Evolution and Environmental and Applied Microbiology
Dr. Livnat Afriat-Jurnou
Mining marine metagenomes revealed a quorum-quenching lactonase with improved biochemical properties that inhibits the food spoilage bacteria Pseudomonas fluorescens
Haramati, R., Dor, S., Gurevich, D., Levy, D., Freund, D., Rytwo, G., Sharon, I., Afriat-Jurnou, L.
2021
Bacterial Quorum-Quenching Lactonase Hydrolyzes Fungal Mycotoxin and Reduces Pathogenicity of Penicillium expansum-Suggesting a Mechanism of Bacterial Antagonism
Shlomit Dor , Dov Prusky, Livnat Afriat-Jurnou
Journal of Fungi
2021
Identification and Characterization of a New Quorum-Quenching N-acyl Homoserine Lactonase in the Plant Pathogen Erwinia amylovora
Sapir Yaar Bar, Shlomit Dor, Mayan Erov, Livnat Afriat-Jurnou
Journal of Agricultural and Food Chemistry
10.1021/acs.jafc.1c00366
10.1021/acs.jafc.1c00366
2021
Directed Enzyme Evolution and Encapsulation in Peptide Nanospheres of Quorum Quenching Lactonase as an Antibacterial Treatment against Plant Pathogen
David Gurevich , Shlomit Dor , Mayan Erov , Yoav Dan , Jehudith Clara Moy , Orly Mairesse , Mery Dafny-Yelin , Lihi Adler-Abramovich , Livnat Afriat-Jurnou
ACS Appl. Mater. Interfaces
2021
Predicting nitroimidazole antibiotic resistance mutations in Mycobacterium tuberculosis with protein engineering
M. Lee B.M, Almeida D.V., Afriat-Jurnou L, Aung H.L., Forde B.M., Hards K., Pidot S.J, Ahmed H.F., A., Mohamed E., Taylor M.C., West N.P, Stinear T.P., Greening C., Beatson S.A., Cook G.M., Nuermberger E.L., Jackson C.J.
Plos Pathogen
2020
New homologues of Brassicaceae water?soluble chlorophyll proteins shed light on chlorophyll binding, spectral tuning and molecular evolution.
Prabahar, V., Jurnou, L. A., Paluy, I., Peleg, Y., & Noy, D.
Febs Journal 2019 Pages febs.15068
2019
"Directed evolution of an endoinulinase from Talaromyces purpureogenus toward efficient production of inulooligosaccharides"
Afriat-Jurnou L, Cohen R, Paluy I, Ben-adiva R, Yadid I.
Biotechnology progress
2018
The role of protein dynamics in the evolution of new enzyme function
Campbell E, Kaltenbach M, Correy GJ, Carr PD, Porebski BT, Livingstone EK, Afriat-Jurnou L, Buckle AM, Weik M, Hollfelder F, Tokuriki N, Jackson CJ
Nature Chemical Biology 2016
2016
Sequence-Structure-Function Classification of a Catalytically Diverse Oxidoreductase Superfamily in Mycobacteria
Ahmed FH, Carr PD, Lee BM, Afriat-Jurnou L, Mohamed AE, Hong NS, Flanagan J, Taylor MC, Greening C, Jackson CJ
J Mol Biol. 2015 Volume 6;427(22):3554-71
2015
Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme.” Nature communication
Tokuriki N, Jackson CJ, Jurnou-Afriat L, Tawfik DS
Nature communications
2012
Reconstructing a missing link in the evolution of a recently diverged phosphotriesterase by active-site loop remodeling
Afriat-Jurnou L; Jackson CJ; Tawfik DS.
Biochemistry 2012 Volume 51 Pages 6047-6055
2012
Conformational sampling, catalysis, and evolution of the bacterial phosphotriesterase.
Jackson CJ, Foo JL, Tokuriki N, Afriat L, Carr PD, Kim HK, Schenk G, Tawfik DS, Ollis DL.
PNAS
2009
The latent promiscuity of newly identified microbial lactonases is linked to recently diverged phosphotriesterase. Biochemistry.
Afriat L, Roodveldt C, Manco G, Tawfik DS
Biochemistry
2006