Enzymes Evolution and Environmental and Applied Microbiology

We are interested in understanding the molecular mechanisms that govern the evolution of new functions in microbial enzymes concerning their biological role and applying scientific insights to solve fundamental and applicative problems using protein engineering.

Dr. Livnat Afriat-Jurnou

Principal Researcher

Former Group Members

Former Group Members

Dr. Ofir Gershoni

Rami Harmati

Sapir Yaar-bar

Keren Nudel

David Gurevich

Guy Or

Mayan Erov

Maria Vetcos



Yadid I, Cohen R, Afriat-Jurnou L, "Improved endoinulinase", MIGAL APPLIED RESEARCH, LTD, PCT/IL2018/050872, 07 Aug 2018.
Afriat-Jurnou L, Erov M, Gurevich D, and Mery Dafny-Yalin. "Stabilized mutants of quorum quenching lactonase as antibacterial treatment for plant pathogens". MIGAL APPLIED RESEARCH, LTD, PCT/IL2020/050673, 17-Jun-2020.
Adler-Abramovich L., Afriat-Jurnou L. “Peptide nanospheres and nanotubes encapsulating quorum quenching lactonase and uses". MIGAL APPLIED RESEARCH US Patent Application No. 63/040,299.
Afriat-Jurnou L., Dov Prusky, "USE OF STABILIZED MUTANTS OF LACTONASE IN TREATMENT OF FUNGI". MIGAL APPLIED RESEARCH. U.S. Patent Application Number 63/126,277, filed December 16, 2020.
Afriat-Jurnou L. Itai Sharon. QUORUM QUENCHING ENZYME, AND METHODS OF USING SAME “,PCT Patent Application No. PCT/IL2022/050792.

Latest Publications

Mining marine metagenomes revealed a quorum-quenching lactonase with improved biochemical properties that inhibits the food spoilage bacteria Pseudomonas fluorescens

Haramati, R., Dor, S., Gurevich, D., Levy, D., Freund, D., Rytwo, G., Sharon, I., Afriat-Jurnou, L.

Bacterial Quorum-Quenching Lactonase Hydrolyzes Fungal Mycotoxin and Reduces Pathogenicity of Penicillium expansum-Suggesting a Mechanism of Bacterial Antagonism

Shlomit Dor , Dov Prusky, Livnat Afriat-Jurnou
Journal of Fungi

Identification and Characterization of a New Quorum-Quenching N-acyl Homoserine Lactonase in the Plant Pathogen Erwinia amylovora

Sapir Yaar Bar, Shlomit Dor, Mayan Erov, Livnat Afriat-Jurnou
Journal of Agricultural and Food Chemistry

Directed Enzyme Evolution and Encapsulation in Peptide Nanospheres of Quorum Quenching Lactonase as an Antibacterial Treatment against Plant Pathogen

David Gurevich , Shlomit Dor , Mayan Erov , Yoav Dan , Jehudith Clara Moy , Orly Mairesse , Mery Dafny-Yelin , Lihi Adler-Abramovich , Livnat Afriat-Jurnou
ACS Appl. Mater. Interfaces

Lab News

Congaratulations to our graduats!

Congratulations to all of our MSC graduates, who received their degrees this week-Rami, Keren and Guy. Also congratulations to Dor and Ariel, Master students in the lab who received their BSc.