Directed Evolution of Enzymes

Dr. Livnat Afriat-Jurnou

Principal Researcher

Dr. Livnat Afriat-Jurnou

Dr. Livnat Afriat-Jurnou
Directed Evolution of Enzymes
972-4-7700403
972-556669613

Enzymes are extremely potent biocatalysts capable of enhancing reaction rates by up to 1019-fold (kcat/knoncat).  Despite their great proficiency, enzymes exhibit a remarkable evolutionary adaptability (evolvability).

Latest Publications

Identification and Characterization of a New Quorum-Quenching N-acyl Homoserine Lactonase in the Plant Pathogen Erwinia amylovora

Sapir Yaar Bar, Shlomit Dor, Mayan Erov, Livnat Afriat-Jurnou
Journal of Agricultural and Food Chemistry
10.1021/acs.jafc.1c00366
2021

Directed Enzyme Evolution and Encapsulation in Peptide Nanospheres of Quorum Quenching Lactonase as an Antibacterial Treatment against Plant Pathogen

David Gurevich , Shlomit Dor , Mayan Erov , Yoav Dan , Jehudith Clara Moy , Orly Mairesse , Mery Dafny-Yelin , Lihi Adler-Abramovich , Livnat Afriat-Jurnou
ACS Appl. Mater. Interfaces
2021

Predicting nitroimidazole antibiotic resistance mutations in Mycobacterium tuberculosis with protein engineering

M. Lee B.M, Almeida D.V., Afriat-Jurnou L, Aung H.L., Forde B.M., Hards K., Pidot S.J, Ahmed H.F., A., Mohamed E., Taylor M.C., West N.P, Stinear T.P., Greening C., Beatson S.A., Cook G.M., Nuermberger E.L., Jackson C.J.
Plos Pathogen
2020

New homologues of Brassicaceae water?soluble chlorophyll proteins shed light on chlorophyll binding, spectral tuning and molecular evolution.

Prabahar, V., Jurnou, L. A., Paluy, I., Peleg, Y., & Noy, D.
Febs Journal 2019 Pages febs.15068
2019