Directed Evolution of Enzymes

Dr. Livnat Afriat-Jurnou

Principal Researcher

Dr. Livnat Afriat-Jurnou

Dr. Livnat Afriat-Jurnou
Dr. Livnat Afriat-Jurnou
Directed Evolution of Enzymes
972-4-7700403
972-556669613
livnatj@migal.org.il

Enzymes are extremely potent biocatalysts capable of enhancing reaction rates by up to 1019-fold (kcat/knoncat).  Despite their great proficiency, enzymes exhibit a remarkable evolutionary adaptability (evolvability).

Latest Publications

Directed Enzyme Evolution and Encapsulation in Peptide Nanospheres of Quorum Quenching Lactonase as an Antibacterial Treatment against Plant Pathogen

David Gurevich , Shlomit Dor , Mayan Erov , Yoav Dan , Jehudith Clara Moy , Orly Mairesse , Mery Dafny-Yelin , Lihi Adler-Abramovich , Livnat Afriat-Jurnou
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Dr. Livnat Afriat-Jurnou
ACS Appl. Mater. Interfaces
2021

Predicting nitroimidazole antibiotic resistance mutations in Mycobacterium tuberculosis with protein engineering

M. Lee B.M, Almeida D.V., Afriat-Jurnou L, Aung H.L., Forde B.M., Hards K., Pidot S.J, Ahmed H.F., A., Mohamed E., Taylor M.C., West N.P, Stinear T.P., Greening C., Beatson S.A., Cook G.M., Nuermberger E.L., Jackson C.J.
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Dr. Livnat Afriat-Jurnou
Plos Pathogen
2020

New homologues of Brassicaceae water?soluble chlorophyll proteins shed light on chlorophyll binding, spectral tuning and molecular evolution.

Prabahar, V., Jurnou, L. A., Paluy, I., Peleg, Y., & Noy, D.
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Dr. Livnat Afriat-Jurnou
Febs Journal 2019 Pages febs.15068
2019

"Directed evolution of an endoinulinase from Talaromyces purpureogenus toward efficient production of inulooligosaccharides"

Afriat-Jurnou L, Cohen R, Paluy I, Ben-adiva R, Yadid I.
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Dr. Livnat Afriat-Jurnou
Biotechnology progress
2018
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